Epitalon

Name: Epitalon
Availability: InStock

10 vial

Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide developed from epithalamin, a serum isolated from the bovine pineal gland. It has been studied for telomerase activation, telomere elongation, melatonin-axis normalisation and broader geroprotective effects in animal and early human research.

Select size

Checking availability…

Researched for

Telomerase activation and telomere lengthening in cell and animal models
Normalisation of pineal melatonin secretion and circadian rhythms
Improved antioxidant enzyme status in ageing research
Potential extension of healthy lifespan markers in animal studies
Support for immune and neuroendocrine function in older subjects
Favourable tolerability profile across reported research

Mechanism of action

Activates telomerase in somatic cells via regulation of the hTERT gene, potentially elongating telomeres and extending cellular replicative lifespan. Also normalises pineal melatonin secretion and modulates gene expression patterns associated with ageing.

Research protocol

Common research protocols use 5–10mg subcutaneously once daily, typically for 10–20 consecutive days, followed by a 4–6 month break before repeating. Some longevity protocols use 2–3 short courses per year.

Half-life

Plasma half-life is short (minutes); functional effects are believed to persist through gene-expression and telomerase changes rather than direct receptor occupancy.

Reconstitution

Reconstitute a 10mg vial with 1–2mL bacteriostatic water for a 5–10mg/mL working concentration. Swirl gently.

Storage

Lyophilised: 2–8°C, stable 18–24 months. Reconstituted: 2–8°C, protect from light, use within 30 days.

Research considerations