Ipamorelin

Name: Ipamorelin
Availability: InStock

2mg vial

Ipamorelin is a selective pentapeptide growth hormone secretagogue (GHRP) that mimics ghrelin's action at the GHS-R1a receptor. It is widely regarded as the cleanest GHRP class member due to its lack of meaningful cortisol, prolactin or aldosterone elevation - a profile that distinguishes it from GHRP-2 and GHRP-6.

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Researched for

Clean pulsatile GH release without cortisol or prolactin elevation
Improved sleep quality, particularly slow-wave architecture
Improved body composition (lean mass support, adipose reduction)
Enhanced recovery and collagen turnover via downstream IGF-1
Synergistic potential when stacked with a GHRH analogue
Preserves natural pulsatile GH rhythm without HGH-style axis suppression

Mechanism of action

Selective agonism of the ghrelin/GHS-R1a receptor on pituitary somatotrophs, triggering acute pulsatile GH release. Frequently stacked with a GHRH analogue (e.g. CJC-1295, Sermorelin, Tesamorelin) for synergistic pulse amplitude.

Research protocol

Common research protocols use 100–300mcg subcutaneously 1–3× daily - typically pre-sleep, post-workout and/or fasted morning - to align with natural GH pulse windows. Cycles run 8–12 weeks on / 4 weeks off.

Half-life

approx. 2 hours.

Reconstitution

Reconstitute a 5mg vial with 2.5mL bacteriostatic water for a 2,000mcg/mL working concentration. Swirl gently.

Storage

Lyophilised: 2–8°C (stable up to 24 months frozen). Reconstituted: 2–8°C, protect from light, use within 28–30 days.

Research considerations

• Mild water retention and injection-site reactions possible at higher doses.
• Best effects typically require GHRH pairing; standalone use produces a smaller GH pulse.
• Chronic IGF-1 elevation should be monitored; avoid sustained supraphysiological dosing.

Other peptides

CJC-1295 / Ipamorelin

Performance

Semaglutide

Metabolic